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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6924729078a7831b5175db155559e1fb743b415ca769e2d161ab396af8101450' 
  AND token = '9rAOthSFtWGrZDXKxgmlH0GOs7VkP0IF/y+H6IB90k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}