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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1d010479286e6e92b7a177ceff830c84315da64ed3dd7306458aa54e419730' 
  AND token = 'A53ALgoALV7yTU9+FlDQfM2ks9x9y2ZAmBwQbCvUWKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}