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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ca08e1d964984f91f01d86db61008b81b2f65bfb36ce00fada2d79eca49627' 
  AND token = 'FG2d3U5N8kOJZAywYZkYhSUIInQNGoPd4waBYCU7jyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}