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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2b99cdce39f29ff8e3b8aacefad92c77775b0a7c3dd3d742e9c0c8db07c08a' 
  AND token = '8sRQ2lw+oD69dfoKdJ9DfSvVDVT6dt5cXSQ4+I42JkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}