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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a85a7246a7c1d321ba564f62caa820cef96234a6b1af536a3b03c6c5149ec7' 
  AND token = '0Tvs00pRK2X35jtKIlW80G6AnVsSjlyTcRFnURXJ3zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}