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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337b83707e55a9fd13aa1a186c490de16069f586ca321e1b395f1313280b47d8' 
  AND token = 'oXDTZ+nGDmEW6CG3/pN9Lr9WKlUeE3XwFtjktLiI23Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}