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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4659232e2fb7fcf8f47aa57860bd229a1b40105a0121f20cb8f86e8047570b03' 
  AND token = 'QoQKFqa0P0geSMoFUfKUDNp+KaBOhq1jIh7sVkercQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}