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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5073fe75a649f402efc8e510c488765c6accdcdb4f95b73881a34c7e0c5365' 
  AND token = 'rfAeQ0SUAOC7Q/NtiJC/+eOH1O5MW6LViZP2yYHEMps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}