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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f639dee2db857e9bbc0815a7bed34a9cdf1bb3c0d64ed8074f22f25636e371c8' 
  AND token = 'f/2xPa2eFWwQiR8cKFXO3cF29CqsI3cqZUAEdSI4/bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}