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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d36de248267dbbb08e91f1c27a0800da26cc4be0c45d9bfeddccecca087a54' 
  AND token = 'Brsd+LzBndujbLBBZhd3YkxUkQlI5AXB48Ryd3PFcJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}