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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4fe0ad935a99d884339f1b3b4b49ab9b1a67b4c5c03ae713216fc4b423b7686' 
  AND token = 'OgRKw/OG2d+x4iqCwSUnn2new3mSGr78X7pyT3ZtR4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}