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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc07576c871c14e74344e53675fe9100a4dea899e4b39f93a1d6d69c713cf303' 
  AND token = '6LPcz11lnmEjaIE5uW1CKvIwxhRTAVOyxh76Thhx/8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}