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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452364747ba9f0dfb26623624575b98cdf9af813d7e68c2fad093d733ffa9dd2' 
  AND token = '2ToEPFeS1HjiJvFL+KzcAeLpjoi4j/MM3bw7+f6LbFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}