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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7373bfcba5f9317260e38ae8de7c7f99cdcd5b7a3de6317cbb18e9ef710e680f' 
  AND token = 'URz2gnkBBjiKkb+VSIQvCTJzHE1KxHYxRb0Nc2/2uSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}