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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0fa72cc7e2a08966154e0a98f57671cd3411d343c915960576ec4dbf321000' 
  AND token = 'QjmFgOffgp+WXFVT4IGg8Q1UQHC28Ndh6JX59CV1T98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}