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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94057e2269e0c5130524558ed94044fa43351308159414656891dda9aa706f2f' 
  AND token = 'EJbsIkA+bE1ajQh7KOR0wrNQO629mwEJHdWJT9Fr+Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}