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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c082bf8d1e992b3df0c2df490a1d21b3d69b35b5e746d4cb63750f4c963a28a' 
  AND token = 'KCmnMz05ys54vf/a5D9NBnPbQdRUgs9cT0jGn+DB7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}