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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc4a148d172f63b86517ea1487e424ac43c33090af2631dabdbeb0ebaa486bf5' 
  AND token = '3kYMaexXVLpnlIWpn5EJK+ccuIc3Ebd8fdaIkw6pxKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}