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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ec96d5d91e44c0af50eca9023fbdf6a11f9ec2813d25daeefb11ec644c6aa2' 
  AND token = 'Q8zTOR8YHv2NOCwf78EdU/dMMtC9vmi74HmhHbuTvO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}