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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5472230b2bf27810a85ab09bd1d4cec4c90241995b27c8ef611b67064d8eb82c' 
  AND token = 'QbQ2z8ADFVKBkqpU0m8hcNlE6NK98QefBZ19OxDJuu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}