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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1626ce720215b8e0c34c5cb32647d5a6c20ddff90fc32a828176a8a0718ea2d4' 
  AND token = 'zHPpc6IJF/6gM5ATgBqNQy2BM1eBe5n/ZGGBFtgRfMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}