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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef0d5ae39625208c8806a8e7c02d2ff442c2848b9e80e1cc52cfc56fb78cd8b' 
  AND token = 'wSMv6OM4SJQTgs+LWsXaHNBX3RP68fVJ7QZG+MweZ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}