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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5528b8db8c22663cdac4742f6a8c989565655068c045e04e01cdefa2116acd' 
  AND token = 'GE7/S5/Yw52cIoAMmNJLd7zFHwgK2o4dKPr8FXGiCMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}