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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86b1d437c1683e5c80982429fecd0a896e715ac59a5b2c18b9f86b3f106e8f7' 
  AND token = 'HO6zCDEA0aAtFfSHjAda7alBtD8ibw3QhUh35OujTuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}