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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '969525c0c6f9194502d721bb66c2e66efee2e257b38ee650be7a37dd8b8d3172' 
  AND token = 'r/kXg1HnXVCEk/Zn+8luoZ3do96HlzZ31tr8mpoHvtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}