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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf5b23b4225ebac9b7f0b238c4ae40b7d5872024c1754a98e2220a08335fb42' 
  AND token = 'UKBLtqr/fQ+0Fc0kyPZWFWgg94N2ROG5KGN6EaBKH08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}