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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1083e46164c7fdf6749a9b140d9747586105d8b3cac768f59a3b08b05b72872b' 
  AND token = '4vVe/eAgV5gQfxYYmN2lu3g/rlr5MB2TgcC16t6zTuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}