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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5544b19095e7eaf740e4e4868b91058f3f5d72079efce7d2a50a9df5898e86c4' 
  AND token = 'MuhumIgwORmVaH6YnH5IMAMtdLRkD1fyylgwl5RIlPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}