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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66220d57a551d41be495d05b3770773971e31b7f1f12f5ff6ca52a2352b7601' 
  AND token = 'EbHxXhhJ6UpKCwhG65bmBKKg9s7+eOaCJslI1s+nG5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}