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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648c2080b10f9b7851ca847f69e1eebe3c56780efae45c92c8ae512e1096c78b' 
  AND token = 'hD0FBfNRzG9rhOLYaxj1H0t3PtuUjh2dJQQktJgItNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}