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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb963cc028c4db3c725a1493d012bcf19d23f8778786f5ed05799e42125b4dd' 
  AND token = 'rJM5Ve2WZQdE4dR2OyCha65155AL+EHRZ0vFpsk7O/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}