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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39464d8e03b6a3d27c8f3584febb14002c23b23ff4a99cbd227c5bad2908b5a' 
  AND token = '6b+ZCNCqQEqmiOxrptriB6B38PsO4rQrObLLbjds4qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}