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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b635c69d427ce529f313db4a5c48c1aed24e8e0f8a0d12361081cedcc060f25e' 
  AND token = 'a1+zmewCjZ2ymrsDCW8vp1hb//JguYeqy36zAb3SfXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}