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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728a110d10b4be77f5613473dd26425063ef55771ceddb8d10c8884945e76c96' 
  AND token = 'msn6J70fPK1dxjdvK6iskjtnai7IYR2fCmp9RxuuosQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}