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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2a8def5ffafa7396725b7bef156f8dc0dba09b18d275364c958099cda48e13' 
  AND token = 'Y1162td2Lspk+vVWJGEFZEvmYjonESbdzshs47ubXpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}