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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cac65361c549a8821d4ec46532eb43f9779572eab11da62b257e2f7b55433e3' 
  AND token = 'nOOX8cCNufQGL2YWBFk3y9fn9qTSmmT/0c89nevxVgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}