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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a80f21ae8b91b6a120f23cc1e684114b54ac8e94b0ce5c45e19da786bc669b2' 
  AND token = 'vGJpctev5ewGjVwHiHtKW66IQNgwNwfJKZMk5+gLtuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}