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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3063290131f1d536cfcf674263105f949f313f5355bc3de88b0f5dfa9e2f2d31' 
  AND token = 'WpHvdUKrnAWP5VqxM8l7MMb2wju4xZ6CVhy49Aye4Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}