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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22738fb288a5a5f954c239b5219b5161a7b78213fcbd1dbbe93e9aa0976527b4' 
  AND token = 'WFCZrbNkWWgenDPwmVwT7cmPecIowAH49lGlpJ3EKbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}