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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f80c629964d32cfb728f712f940c41115d94cce01cbc77cd4994764f25fa84' 
  AND token = '2rsODrZE2uPRMUuWq4HghMv1Fg8s7b5zjjSDKcduYDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}