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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a36012b372cd53b848d5ad79e2afc0557d6127000cf5d3d1940ad01637d6f7ed' 
  AND token = '+UV/gYeqa8dg5lpWmYWuttvE53q2Do1Eu4m+2DIyaJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}