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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3124b22fa108c50f39c6774b11feff0a65fcc268611147f59b0693b7a743177' 
  AND token = 'HdQ6UadC3p5xXZGgyTEXZKRaFU+zVa8guuWmkK7Qy7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}