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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee44e2a18b50bc129cc96b05d4a46c5347c8e232b88db4d9c8574ac03d47a544' 
  AND token = 'oVVzFB7KBUAhG6NqNBQFjdBdYTI0Wo9TqQ0SrR7NZoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}