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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4181bec3cd7026714c78bcf602ccc964a16e7228e27bf8bc15547e9eea8e583c' 
  AND token = 'r9zdpqbDoywCD0ZCn0zsr/TVSshGj3PQd224J1bR5TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}