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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080ad1b983946d6a1cb948e98b9b00599a511e704d2c1faca6237da3eba6a062' 
  AND token = 'M2Og5+fY3Sb1U4ACB1WK23BegbPn16X4vVEGaxV9qSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}