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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e399a450e4db7f2b43102bd8985a3a6c206e6a04e7aa82d7f4a2b039009d54' 
  AND token = 'rFYSIhL2NULjlFX8Zme2ismxaroMomr1zmGMC/bybUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}