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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33effbf66a20f7fbe2fe5d969c033ed753ce945da464642166a6d54eff20706c' 
  AND token = '6zFIMhc5UCMqALCtwIHC9p5xB0OqdZKyWZI3c7GvDN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}