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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6609b80f168d8626b2f0406e4d9fda5b8711467d5bf4a2541f8604c0c46ef2' 
  AND token = 'XuXUyR3Kzpy0vjDtw6gdfNXJRzmCYIvEmlLP3KAxdYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}