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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2863f05420dc54a4a04b5e75c849b6cd1c838ee586f0658226ad93c7b8a23dc0' 
  AND token = 'mXJQ1DB4M/dxcxShGWk4LDxJ08kOtapZi5EwUTLM1g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}