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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8ef8fc51123e79d57a5ff3e730a1e0a2282e36bbc96852b514974a67416fb4' 
  AND token = 'wQo1ZC4Z8FmPkrMBLSVIf80uARywGI11buQzduzOYrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}